I am a LUA breeder
LUA Dalmatians do not suffer from Hyperuricosuria
LUA stands for Low Uric Acid
I am very proud to call myself a LUA (low uric acid) Dalmatian breeder as this gene is life changing for the breed. It is my dream that one day, every puppy i help bring into this world will be free of Hyperuricosuria.
Hyperuricosuria effects how the body deals with -or more accurately, does not deal with- a specific waste product, purines, found in all food. The body does not have the ability to "delete" this waste and so it travels down to settle inside the bladder. It then mixes with the urine to form salt stones which can cause painful blockages. Sadly, this can happen even if you do everything right.
A very smart breeder discovered that the only way to get rid of this main health condition in the breed was to outcross to another breed, and it worked! He added a pointer into the mix in 1970 and only Dalmatians have been used since. The dogs that do not inherit the unhealthy Hyperuricosuria gene are known as LUA as the uric acid in their bodies are of a normal, average, low, healthy range and are free from dietary restrictions and the threat of stones.
A very good read if you want to understand the LUA project a little better
https://thebark.com/content/dna-test-helps-dalmatians#:~:text=Each time one of these,and 50 percent are HUA